Description

Udpga Trisodium Salt CAS NO 63700-19-6 is a high-purity biochemical reagent widely used as a critical cofactor in enzymatic reactions, particularly for glucuronidation studies. Its consistent quality and stability are essential for reliable research and development outcomes in drug metabolism and toxicology. This product is primarily targeted at pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions conducting advanced biochemical assays.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Serves as a co-substrate for UDP-glucuronosyltransferase (UGT) enzymes in in vitro glucuronidation assays to assess drug metabolite profiles.
• Enzyme Kinetics Research: Used to determine kinetic parameters (Km, Vmax) of UGT isoforms, facilitating the study of enzyme specificity and inhibition.
• Toxicology and Safety Assessment: Employed in assays to investigate the detoxification pathways of xenobiotics and endogenous compounds via glucuronide conjugation.
• Biochemical Reagent Manufacturing: Acts as a key raw material in the formulation of diagnostic kits and enzyme assay systems for clinical and research use.
• Academic Research: Supports fundamental research in biochemistry and molecular biology focused on phase II drug metabolism and conjugation reactions.

Basic Information

Product Name	Udpga Trisodium Salt
CAS No.	63700-19-6
Molecular Formula	C15H21N2Na3O18P2
Molecular Weight	664.22 g/mol (anhydrous basis)
Synonyms	UDP-Glucuronic Acid Trisodium Salt; Uridine 5'-Diphosphoglucuronic Acid Trisodium Salt; UDP-α-D-Glucuronic Acid Trisodium Salt; UDP-GlcA Trisodium Salt; UDPGA Na3; 5'-UDP-Glucuronate Trisodium Salt; Uridine Diphosphate Glucuronic Acid Trisodium Salt
EINECS	Contact for details

Quality Control

Our Udpga Trisodium Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high performance in sensitive biochemical applications. Each lot is tested for identity, purity, and biological activity. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), water content, and enzymatic activity is provided with every shipment, supporting compliance with rigorous research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Enzymatic Activity	Conforms to functional assay
pH (1% Solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.