Description

Boc-3,5-Diiodo-Tyr(3'-Bromo-Bzl)-Oh is a protected, halogenated tyrosine derivative, specifically engineered for advanced peptide synthesis and medicinal chemistry research. This compound is a critical building block for the development of novel peptide-based pharmaceuticals and biochemical probes, offering precise control over molecular structure. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating targeted therapeutics and diagnostic agents.

Application

• Peptide Synthesis: Serves as a key protected amino acid intermediate for the solid-phase and solution-phase synthesis of complex, iodinated, and bromobenzylated peptides.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the development of peptide hormone analogs, receptor ligands, and enzyme inhibitors.
• Radiopharmaceutical Precursor: The diiodo-tyrosine structure provides a potential platform for radioiodination, useful in creating imaging agents for diagnostic purposes.
• Bioconjugation: Acts as a specialty linker or modified residue for attaching peptides to other molecules, surfaces, or fluorescent tags in probe development.
• Academic & Industrial Research: Employed in biochemical research to study protein-protein interactions, signal transduction pathways, and enzyme mechanisms.
• Pharmaceutical Intermediates: A high-purity intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs) with specific halogenated motifs.

Basic Information

Item	Detail
Product Name	Boc-3,5-Diiodo-Tyr(3'-Bromo-Bzl)-Oh
CAS No.	63570-43-4
Molecular Formula	C21H22BrI2NO5
Molecular Weight	743.12 g/mol
Synonyms	Boc-3,5-Diiodotyrosine(3'-Bromobenzyl) Ester; N-(tert-Butoxycarbonyl)-3,5-diiodo-O-(3'-bromobenzyl)-L-tyrosine; Boc-Tyr(3,5-I2, 3'-Br-Bzl)-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-[4-hydroxy-3,5-diiodo-2-(3-bromobenzyloxy)phenyl]propanoic acid; Boc-L-3,5-Diiodotyrosine(3-Bromobenzyl) Ether; Protected Diiodotyrosine Derivative; 63570-43-4
EINECS	Contact for details

Quality Control

Every batch of Boc-3,5-Diiodo-Tyr(3'-Bromo-Bzl)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a desiccated environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.