Description

Cefazedone Sodium Salt CAS NO 63521-15-3 is a semi-synthetic, first-generation cephalosporin antibiotic in its sodium salt form, offering enhanced stability and solubility for pharmaceutical formulation. This compound is valued for its potent bactericidal activity against a broad spectrum of Gram-positive and some Gram-negative bacteria. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of injectable antibiotic preparations and as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of sterile injectable antibiotic formulations.
• Research & Development: Used as a biochemical tool in microbiological studies and for investigating bacterial resistance mechanisms.
• Reference Standard: Serves as a high-purity calibrant in Quality Control (QC) laboratories for HPLC, UV, and microbiological assay methods.
• Veterinary Medicine: Employed in the development of antibacterial treatments for livestock and companion animals.
• Intermediate Synthesis: Acts as a key starting material or intermediate for the synthesis of more complex cephalosporin derivatives.

Basic Information

Product Name	Cefazedone Sodium Salt
CAS No.	63521-15-3
Molecular Formula	C₁₉H₁₆N₄NaO₆S₂
Molecular Weight	483.47 g/mol
Synonyms	Cefazedone Sodium; Sodium Cefazedone; Cefazedone Na; Refosporen; SKF 59962; 7-[(2,3-Dihydro-2-thienyl)acetamido]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Cefazedone Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) providing batch-specific results for all critical parameters is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	6.0 - 8.0
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.