Description

Technetium Tc 99M Etidronate is a diagnostic radiopharmaceutical agent used in nuclear medicine imaging. Its core value lies in its ability to target and visualize skeletal structures, providing critical diagnostic information for bone-related pathologies. This compound is essential for hospitals, diagnostic imaging centers, and radiopharmacies specializing in bone scintigraphy procedures to detect metastases, infections, and other abnormalities.

Application

• Bone Scintigraphy (Bone Scan): Primary diagnostic tool for detecting skeletal metastases from cancers such as breast, prostate, and lung cancer.
• Osteomyelitis Diagnosis: Used to identify and localize bone infections, particularly in complex cases.
• Evaluation of Prosthetic Joints: Assesses loosening or infection associated with artificial joints.
• Paget's Disease Assessment: Aids in evaluating the extent and activity of this chronic bone disorder.
• Trauma and Fracture Evaluation: Useful for identifying stress fractures and other traumatic bone injuries not visible on standard X-rays.
• Metabolic Bone Disease Research: Serves as a tracer in clinical research studies investigating bone turnover and metabolic conditions.

Basic Information

Product Name	Technetium Tc 99M Etidronate
CAS No.	63347-65-9
Molecular Formula	C2H8O7P2 • 99mTc
Molecular Weight	Contact for details
Synonyms	Technetium-99m Etidronate; 99mTc-Etidronate; 99mTc-HEDP; Technetium Tc 99m Oxidronate; Technetium (99mTc) Etidronate; Tc-99m HEDP; Bone Scan Agent; Radpharm Tc-99m HEDP; Oxidronic acid, technetium-99m complex
EINECS	Contact for details

Quality Control

Every batch of Technetium Tc 99M Etidronate is manufactured and tested under strict radiopharmaceutical Good Manufacturing Practices (GMP). Quality control includes rigorous testing for radiochemical purity, radionuclidic purity, pH, sterility, and apyrogenicity to ensure compliance with international pharmacopeial standards (e.g., USP, Ph. Eur.). A comprehensive Certificate of Analysis (COA) detailing all release specifications is provided with each shipment.

Storage

Preserve in the original, appropriately shielded, tightly closed container, protected from all light exposure. Store at controlled room temperature (15-25°C) unless otherwise specified by the manufacturer. Due to the radioactive nature of Technetium-99m, follow all applicable radiation safety protocols, including time, distance, and shielding principles. The product must be used within its calibrated expiry date/time.

Specification

Item	Specification
Appearance	Clear, colorless to slightly pale yellow solution
pH	5.0 - 7.0
Radiochemical Purity (HPLC/TLC)	≥ 95.0%
Radionuclidic Purity (Gamma Spectroscopy)	≥ 99.9% 99mTc
Identification (Gamma Ray Spectrum)	Complies
Sterility Test	Sterile
Bacterial Endotoxins (LAL)	< 175 EU/Vial
Radioactivity Concentration	As per calibration certificate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.