Description

(5R)-5-(Phenylmethyl)-2-Pyrrolidinone is a chiral lactam derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate for the development of high-value, optically active pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug candidates.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries, catalysts, and ligands used in stereoselective transformations.
• Agrochemical Research: Building block for developing novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological research for developing new synthetic routes and studying reaction mechanisms.

Basic Information

Product Name	(5R)-5-(Phenylmethyl)-2-Pyrrolidinone
CAS No.	63328-11-0
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	(R)-5-Benzyl-2-pyrrolidinone; (5R)-5-Benzylpyrrolidin-2-one; (R)-(-)-5-Benzyl-2-pyrrolidinone; (R)-5-Benzyl-2-oxopyrrolidine; (R)-5-(Phenylmethyl)-2-pyrrolidinone; L-5-Benzyl-2-pyrrolidinone; (R)-5-Benzyl-dihydro-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our (5R)-5-(Phenylmethyl)-2-Pyrrolidinone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to meet the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and enantiomeric excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.