Description

Pokeweed Mitogen is a potent lectin derived from the roots of the *Phytolacca americana* plant, widely recognized for its ability to induce lymphocyte proliferation. This biological activity makes it an invaluable tool for immunological research and diagnostic applications. It is essential for life science researchers, pharmaceutical developers, and diagnostic kit manufacturers requiring a reliable, high-purity mitogen for cell culture and assay systems.

Application

• Immunological Research: Used as a non-specific T-cell and B-cell mitogen to stimulate lymphocyte proliferation in cell culture studies.
• Diagnostic Assays: Serves as a positive control in lymphocyte transformation tests (LTT) and other immune function assays.
• Cell Biology Studies: Employed to study cell cycle progression, signal transduction pathways, and apoptosis in immune cells.
• Vaccine Adjuvant Research: Investigated for its potential to enhance immune responses in preclinical vaccine development.
• Biomarker Discovery: Used to activate immune cells for proteomic and genomic analysis to identify novel biomarkers.
• Quality Control in Biomanufacturing: Acts as a standard reagent to test the responsiveness of cells used in bioprocessing.

Basic Information

Product Name	Pokeweed Mitogen
CAS No.	63231-57-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PWM; Phytolacca americana Mitogen; Pokeweed Lectin; Pa-1; Pa-2; *Phytolacca americana* Lectin; Lymphocyte Mitogen (Pokeweed)
EINECS	Contact for details

Quality Control

Our Pokeweed Mitogen is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is characterized for mitogenic activity using standard lymphocyte proliferation assays. Certificates of Analysis (COA) detailing purity, protein content, and biological potency are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Protein Content (Biuret)	≥ 90%
Purity (SDS-PAGE)	Major band corresponding to PWM
Biological Activity	Stimulates human lymphocyte proliferation at defined concentrations
Endotoxin (LAL)	< 1.0 EU/mg
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.