Description

n-(2-Acetoxybenzoyl)-L-Proline is a specialized chiral organic compound that serves as a key intermediate in advanced pharmaceutical synthesis. Its value lies in its precise molecular architecture, which is critical for constructing active pharmaceutical ingredients (APIs) with high stereochemical purity. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical industries developing new therapeutic agents, particularly in areas requiring proline-derived or acetyl salicylate-based motifs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of enzyme inhibitors where the L-proline moiety is a key pharmacophore.
• Peptidomimetic Synthesis: Serves as a constrained amino acid derivative for creating peptide analogs with enhanced metabolic stability.
• Anti-inflammatory Agent Development: Explored in research related to modified salicylate derivatives with potential therapeutic activity.
• Chiral Auxiliary or Ligand: Can be utilized in asymmetric synthesis due to its defined stereocenter derived from L-proline.
• Bioconjugation Chemistry: Acts as a functionalized linker molecule for attaching pharmacophores or labels in bioconjugate platforms.

Basic Information

Item	Details
Product Name	n-(2-Acetoxybenzoyl)-L-Proline
CAS No.	63203-64-5
Molecular Formula	C14H15NO5
Molecular Weight	277.27 g/mol
Synonyms	L-Proline, N-(2-acetoxybenzoyl)-; 2-Acetoxybenzoic Acid L-Proline Amide; N-(2-Acetyloxybenzoyl)-L-proline; N-(2-Acetoxybenzoyl)proline; Aspirin-Proline Conjugate; Acetylsalicyloyl-L-proline; ASL-Pro; (S)-1-(2-Acetoxybenzoyl)pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-(2-Acetoxybenzoyl)-L-Proline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing specific results for identity, assay, and purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.