Description

3-[[2-(2,5-Dioxo-1-Pyrrolidinyl)Ethyl]Phenylamino]Propanenitrile is a specialized heterocyclic organic compound featuring a maleimide linker and a nitrile functional group. This molecular structure makes it a valuable high-purity intermediate for the synthesis of advanced materials and bioactive molecules. It is primarily sought by pharmaceutical R&D and specialty chemical manufacturers for creating targeted conjugates and polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted drug conjugates and antibody-drug conjugates (ADCs) via its maleimide group for selective thiol coupling.
• Bioconjugation Reagent: Used in proteomics and bioassay development for labeling peptides, proteins, and antibodies with fluorescent or other reporter tags.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the production of specialty polymers, hydrogels, and smart materials.
• Material Science: Employed in surface modification and the creation of functional coatings with specific adhesion or release properties.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new synthetic pathways in medicinal and organic chemistry.

Basic Information

Product Name	3-[[2-(2,5-Dioxo-1-Pyrrolidinyl)Ethyl]Phenylamino]Propanenitrile
CAS No.	63133-76-6
Molecular Formula	C15H15N3O2
Molecular Weight	269.30 g/mol
Synonyms	N-(2-Cyanoethyl)-N-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]aniline; 3-({2-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]phenyl}amino)propanenitrile; 1-[2-(N-Phenyl-N-2-cyanoethylamino)ethyl]maleimide; Maleimide-PEG2-C2-cyano; Aniline, N-(2-cyanoethyl)-N-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]-
EINECS	Contact for details

Quality Control

Our production of 3-[[2-(2,5-Dioxo-1-Pyrrolidinyl)Ethyl]Phenylamino]Propanenitrile adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.