Description

D-Prolinamide is a high-purity, non-natural amino acid derivative characterized by its specific D-configuration, which is essential for advanced chiral synthesis and research. This compound serves as a critical chiral building block and intermediate in the development of pharmaceuticals, agrochemicals, and bioactive peptides. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure components for asymmetric synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other bioactive molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate proline analogs, influencing peptide conformation and stability.
• Agrochemical Research: Serves as a building block for developing chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel chiral organocatalysts and ligands for asymmetric transformations.
• Biochemical Research: Utilized as a standard or reagent in enzymatic studies and metabolic pathway investigations involving proline metabolism.
• Fine Chemical Synthesis: An important intermediate for producing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	D-Prolinamide
CAS No.	62937-45-5
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(R)-Pyrrolidine-2-carboxamide; D-2-Pyrrolidinecarboxamide; (R)-2-Carbamoylpyrrolidine; (R)-Proline amide; D-Pro-NH2; (R)-Prolinamide; Prolinamide, D-; (2R)-Pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our D-Prolinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.