Description

Acetamide, n-(4-Cyanophenyl)-2,2,2-Trifluoro- CAS NO 62926-88-9 is a specialized trifluoroacetamide derivative featuring a cyano-substituted phenyl ring, serving as a high-value synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, where its unique trifluoromethyl and nitrile functionalities enable precise molecular modifications. It is primarily sought by pharmaceutical, agrochemical, and advanced material scientists for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring trifluoromethyl or cyano groups for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and biological activity.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry: Valuable synthon for introducing the trifluoroacetamide moiety into more complex molecular architectures in organofluorine chemistry.

Basic Information

Item	Details
Product Name	Acetamide, n-(4-Cyanophenyl)-2,2,2-Trifluoro-
CAS No.	62926-88-9
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	N-(4-Cyanophenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(4-cyanophenyl)acetamide; 4'-(Trifluoroacetylamino)benzonitrile; p-Cyanophenyltrifluoroacetamide; α,α,α-Trifluoro-N-(4-cyanophenyl)acetamide; 4-Cyanoanilinium trifluoroacetate (derivative); TFAA-4-CN-Ph; TFA-4-Cyanophenylamide
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-(4-Cyanophenyl)-2,2,2-Trifluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting R&D and commercial standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.