Description

Cefoperazone Sodium is a semi-synthetic, broad-spectrum third-generation cephalosporin antibiotic formulated as a stable sodium salt. This compound is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa. It is essential for pharmaceutical manufacturers and research institutions developing injectable antibiotic formulations, active pharmaceutical ingredients (APIs), and reference standards for quality control.

Application

• Pharmaceutical API Manufacturing: Primary use as the active ingredient in sterile injectable antibiotic preparations.
• Veterinary Medicine: Formulation of antibacterial treatments for livestock and companion animals.
• Research & Development: Used as a reference standard in microbiological assays, pharmacokinetic studies, and drug resistance research.
• Hospital Compounding: For the preparation of specific dosage forms in clinical settings where commercial preparations are unavailable.
• Biochemical Research: Study of β-lactam antibiotic mechanisms of action and bacterial cell wall synthesis inhibition.

Basic Information

Product Name	Cefoperazone Sodium
CAS No.	62893-20-3
Molecular Formula	C25H26N9NaO8S2
Molecular Weight	667.65 g/mol
Synonyms	Cefoperazone Sodium Salt; T-1551; Cefobid; Cefoperazone Na; (6R,7R)-7-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium; Sodium (6R,7R)-7-[(R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
EINECS	263-690-7

Quality Control

Our Cefoperazone Sodium is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	4.5 - 6.5
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.