Description

n-Trifluoroacetyl (S)-Amphetamine is a chiral, fluorinated derivative of amphetamine, serving as a key synthetic intermediate and analytical reference standard. This compound is of significant value in pharmaceutical research and development, particularly for creating novel active pharmaceutical ingredients (APIs) and for metabolic studies. It is primarily utilized by research institutions, pharmaceutical companies, and forensic laboratories engaged in neuropharmacology, analytical method development, and the synthesis of specialized chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel psychoactive substances and fluorinated pharmaceutical candidates.
• Analytical Reference Standard: Used for method development, validation, and quality control in chromatographic analysis (HPLC, GC-MS) for forensic and clinical toxicology.
• Metabolic Studies: Employed as a stable-labeled or derivatized analog to investigate the metabolic pathways and pharmacokinetics of amphetamine-related compounds.
• Biochemical Research: Serves as a ligand or probe in receptor-binding assays and studies targeting monoamine transporters and neurotransmitter systems.
• Chemical Synthesis: Acts as a protected or activated form of (S)-amphetamine for further selective chemical modifications in organic synthesis.

Basic Information

Product Name	n-Trifluoroacetyl (S)-Amphetamine
CAS No.	62840-99-7
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	(S)-1-Phenyl-2-(trifluoroacetamido)propane; (S)-N-(1-Phenylpropan-2-yl)-2,2,2-trifluoroacetamide; (S)-Amphetamine Trifluoroacetamide; (S)-α-Methylphenethylamine Trifluoroacetamide; TFAA derivative of (S)-Amphetamine; (S)-N-Trifluoroacetylamphetamine; (S)-N-TFA-amphetamine
EINECS	Contact for details

Quality Control

Our n-Trifluoroacetyl (S)-Amphetamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and chiral integrity, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, chiral excess, and identity are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.