Description

Methyl Trifluoromethylcarbamate is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethylcarbamate group, enabling the efficient introduction of fluorine-containing motifs into target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the trifluoromethyl group can improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and coatings with unique surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to install the -OC(O)NHCF3 moiety, a valuable handle for further chemical transformations.
• Fluorine Chemistry Research: Essential reagent in academic and industrial laboratories focused on exploring new methodologies for C-F and C-N bond formation.

Basic Information

Product Name	Methyl Trifluoromethylcarbamate
CAS No.	62765-22-4
Molecular Formula	C3H4F3NO2
Molecular Weight	143.06 g/mol
Synonyms	Methyl N-(trifluoromethyl)carbamate; Carbamic acid, N-(trifluoromethyl)-, methyl ester; Methyl trifluoromethylcarbamate; Methyl (trifluoromethyl)carbamate; Methyl N-trifluoromethylcarbamate; Trifluoromethylcarbamic acid methyl ester; Methyl ester of trifluoromethylcarbamic acid
EINECS	Contact for details

Quality Control

Our Methyl Trifluoromethylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.