Description

L-Cysteine,S-(Triphenylmethyl)-, Methyl Ester, Hydrochloride (1:1) is a protected derivative of the amino acid L-cysteine, where the thiol group is blocked by a triphenylmethyl (trityl) group and the carboxylic acid is esterified. This compound is critically important as a key synthetic intermediate in the production of peptides and other bioactive molecules, offering precise control over chemical reactivity. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in advanced organic synthesis and peptide chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Bioconjugation Chemistry: Used to introduce protected cysteine residues for site-specific protein and antibody modifications.
• Research & Development: Serves as a standard reagent in academic and industrial labs for studying sulfur chemistry and developing new synthetic methodologies.
• Fine Chemical Synthesis: Employed in the preparation of specialized thiol-containing compounds where selective deprotection is required.
• Reference Standard: Utilized as a high-purity analytical standard for quality control in related chemical processes.

Basic Information

Product Name	L-Cysteine,S-(Triphenylmethyl)-, Methyl Ester, Hydrochloride (1:1)
CAS No.	62675-68-7
Molecular Formula	C23H24ClNO2S
Molecular Weight	414.0 g/mol
Synonyms	L-Cysteine methyl ester trityl hydrochloride; S-Trityl-L-cysteine methyl ester hydrochloride; (R)-2-Amino-3-((trityl)thio)propanoic acid methyl ester hydrochloride; Methyl S-trityl-L-cysteinate hydrochloride; NSC 334368; Fmoc-Cys(Trt)-OH methyl ester precursor; Cysteine protecting group reagent; Trityl-cysteine-OMe·HCl
EINECS	Contact for details

Quality Control

Our L-Cysteine,S-(Triphenylmethyl)-, Methyl Ester, Hydrochloride (1:1) is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency suitable for research and synthesis. We adhere to cGMP principles where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each batch to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.