Description

Secretin (4-27) CAS NO 62643-35-0 is a synthetic peptide fragment corresponding to the active C-terminal region of the endogenous gastrointestinal hormone secretin. This high-purity compound is critical for research and development in the fields of endocrinology and gastroenterology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers investigating pancreatic function, gastric acid secretion, and related therapeutic pathways.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of secretin receptor (SCTR) activation, signaling pathways, and physiological responses.
• Diagnostic Development: Serves as a key component in the development and calibration of in vitro diagnostic assays for pancreatic and gastrointestinal disorders.
• Biochemical Tool: Employed in cell-based assays and tissue studies to stimulate bicarbonate-rich secretion from the pancreas and bile ducts.
• Drug Discovery: Acts as a lead compound or biological probe for designing novel therapeutics targeting metabolic and digestive diseases.
• Academic & Clinical Studies: Utilized in university and hospital laboratories to explore the role of secretin in digestion, water homeostasis, and potential neurological effects.

Basic Information

Product Name	Secretin (4-27)
CAS No.	62643-35-0
Molecular Formula	C128H220N44O39
Molecular Weight	3054.4 g/mol
Synonyms	Secretin (human); Secretin, human; HSDGTFTSELSRLREGARLQRLLQGLV; Porcine Secretin (4-27); Synthetic Secretin Fragment; Gastrointestinal Peptide; SCT; SECR_HUMAN fragment.
EINECS	Contact for details

Quality Control

Our Secretin (4-27) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.