Description

Sodium Propionate-1-13C CAS NO 62601-06-3 is a stable isotope-labeled derivative of sodium propionate, where the carbon at the 1-position is the carbon-13 isotope. This compound is essential for advanced analytical and research applications requiring precise molecular tracing and quantification. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, metabolic research, and food safety sectors for use as an internal standard in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification in LC-MS and GC-MS analyses of propionate and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Used in 13C isotopic labeling studies to investigate propionate metabolism, gluconeogenesis, and other biochemical pathways in vivo and in vitro.
• Pharmaceutical Impurity Profiling & PK/PD Studies: Serves as a critical reference standard in the development and validation of methods for analyzing drug substances and monitoring pharmacokinetics.
• Food & Feed Additive Analysis: Enables precise measurement of sodium propionate levels in food preservation and animal feed products for regulatory compliance and safety.
• NMR Spectroscopy: Acts as a labeled standard for nuclear magnetic resonance studies, aiding in structural elucidation and dynamic process analysis.
• Clinical Diagnostics: Facilitates the accurate detection of metabolic disorders, such as propionic acidemia, through stable isotope dilution techniques.

Basic Information

Product Name	Sodium Propionate-1-13C
CAS No.	62601-06-3
Molecular Formula	13C C2H5NaO2 or C3H5NaO2 (with 13C at position 1)
Molecular Weight	97.05 g/mol (for 13C labeled form)
Synonyms	Propionic-1-13C Acid Sodium Salt; Sodium Propanoate-1-13C; [1-13C]Sodium Propionate; 13C-Labeled Sodium Propionate; NSC 77625; Sodium Propionate (1-13C); Sodium [1-13C]propionate
EINECS	Contact for details

Quality Control

Every batch of Sodium Propionate-1-13C is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure product integrity, including isotopic enrichment (Atom % 13C), chemical purity, and identity confirmation. A Certificate of Analysis (COA) detailing specifications such as assay by HPLC, isotopic purity by NMR or MS, and residual solvent content is supplied with each shipment. Our quality commitment aligns with the needs of cGMP and ISO-guided research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is hygroscopic (moisture-sensitive). For long-term stability, keep the container tightly sealed in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Isotopic Enrichment	≥99 atom % 13C
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.