Description

2-Amino-3-Chloro-5-Cyanobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring amino, chloro, cyano, and trifluoromethyl substituents. This unique combination of functional groups makes it a versatile and critical building block for synthesizing complex molecules, particularly in advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as charge-transport materials, organic light-emitting diodes (OLEDs), and liquid crystals.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments, where its substituted aniline structure contributes to color properties and fastness.
• Cross-Coupling Reactions: The chloro and amino groups make it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to construct complex biaryl structures.

Basic Information

Product Name	2-Amino-3-Chloro-5-Cyanobenzotrifluoride
CAS No.	62584-25-2
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	3-Chloro-2-amino-5-cyanobenzotrifluoride; 2-Amino-3-chloro-α,α,α-trifluoro-p-tolunitrile; 2-Amino-α,α,α-trifluoro-3-chloro-5-cyanotoluene; 3-Chloro-2-amino-α,α,α-trifluoro-p-tolunitrile; Benzonitrile, 2-amino-3-chloro-5-(trifluoromethyl)-; 2-Amino-3-chloro-5-(trifluoromethyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Cyanobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.