Description

3-(Trifluoromethyl)-4-Chlorobenzamide is a high-purity fluorinated aromatic building block of significant industrial importance. This compound serves as a critical intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its unique trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers and liquid crystals that require fluorinated aromatic units.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and other transformations to create complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-(Trifluoromethyl)-4-Chlorobenzamide
CAS No.	62584-23-0
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)benzamide; 3-Trifluoromethyl-4-chlorobenzamide; 4-Chloro-alpha,alpha,α-trifluoro-m-toluamide; 4-Chloro-3-trifluoromethylbenzamide; 62584-23-0; m-Trifluoromethyl-p-chlorobenzamide; Benzamide, 4-chloro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-4-Chlorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.