Description

Boc-Lys(2-Chloro-Z)-Oh T-Butylamine is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound is a critical building block for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, offering orthogonal protection strategies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and biochemical tools. Its specific protection scheme allows for selective deprotection, enabling the construction of sophisticated molecular architectures with high precision.

Application

• Peptide Synthesis: A key intermediate in the synthesis of custom and complex peptides for research and drug discovery.
• Pharmaceutical Intermediates: Serves as a crucial building block in the development of active pharmaceutical ingredients (APIs), particularly for oncology and metabolic disease targets.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for antibody-drug conjugates (ADCs) and other targeted therapies.
• Chemical Biology Probes: Employed in the creation of labeled or modified peptides for studying protein-protein interactions and enzyme activity.
• Process Development: Utilized in scale-up and process optimization for the commercial manufacturing of peptide-based therapeutics.
• Academic Research: Fundamental research tool in university and institutional labs for exploring new synthetic methodologies and peptide chemistry.

Basic Information

Product Name	Boc-Lys(2-Chloro-Z)-Oh T-Butylamine
CAS No.	62559-79-9
Molecular Formula	C₂₅H₄₀ClN₃O₆
Molecular Weight	514.06 g/mol
Synonyms	Nα-Boc-Nε-(2-Chlorobenzyloxycarbonyl)-L-lysine t-Butylamine Salt; Boc-Lys(2-Cl-Z)-OH·t-BuNH₂; (2S)-6-[[(2-Chlorophenyl)methoxy]carbonylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid - 2-methylpropan-2-amine (1:1); t-Butylamine Nα-Boc-Nε-(2-Cl-Z)-L-lysinate; Boc-Lys(2-Chloro-Cbz)-OH tert-Butylamine Salt; Nα-(tert-Butoxycarbonyl)-Nε-[N-(2-chlorobenzyloxycarbonyl)]-L-lysine tert-butylamine salt
EINECS	Contact for details

Quality Control

Our Boc-Lys(2-Chloro-Z)-Oh T-Butylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.