Description

(S)-5-(Aminomethyl)-3-(3-Fluoro-4-Iodophenyl)Oxazolidin-2-One CAS NO 62543-03-7 is a high-purity, chiral oxazolidinone derivative, a critical advanced pharmaceutical intermediate (API) in modern drug discovery. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel antibacterial and central nervous system (CNS) active agents. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics, particularly those targeting resistant bacterial strains and neurological disorders.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel oxazolidinone-class antibiotics, such as linezolid and tedizolid analogs.
• Antibacterial Research: Serves as a core structural motif in medicinal chemistry programs aimed at discovering new agents against multidrug-resistant Gram-positive bacteria.
• CNS Drug Development: Utilized in research for potential neurological and psychiatric therapeutics due to the pharmacophore's activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce specific three-dimensional configurations into target molecules.
• Process Chemistry & Scale-Up: Used in the development and optimization of commercial-scale manufacturing routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical production.

Basic Information

Item	Detail
Product Name	(S)-5-(Aminomethyl)-3-(3-Fluoro-4-Iodophenyl)Oxazolidin-2-One
CAS No.	62543-03-7
Molecular Formula	C10H10FIN2O2
Molecular Weight	336.10 g/mol
Synonyms	(S)-5-(Aminomethyl)-3-(3-Fluoro-4-iodophenyl)-2-oxazolidinone; (3S)-5-(Aminomethyl)-3-(3-fluoro-4-iodophenyl)-1,3-oxazolidin-2-one; (S)-3-(3-Fluoro-4-iodophenyl)-5-(aminomethyl)oxazolidin-2-one; Linezolid Intermediate; Oxazolidinone Derivative; Antibacterial Intermediate; Chiral Oxazolidinone Building Block
EINECS	Contact for details

Quality Control

Our (S)-5-(Aminomethyl)-3-(3-Fluoro-4-Iodophenyl)Oxazolidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting regulatory compliance and your internal quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.