Description

Hemoglobin Alberta is a specific variant of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This compound is of significant interest for biochemical research and diagnostic development due to its unique structural and functional properties. It serves as a critical reagent for scientists and manufacturers in the fields of hematology research, clinical diagnostics, and the development of blood-based analytical standards.

Application

• Biochemical Research: Used as a model protein in studies of hemoglobinopathies, oxygen-binding kinetics, and protein structure-function relationships.
• Diagnostic Reagent Manufacturing: Serves as a key component in the production of calibrators and controls for hematology analyzers and point-of-care testing devices.
• Clinical Standard Development: Essential for creating reference materials used to ensure accuracy and standardization in blood gas and co-oximetry testing.
• Pharmaceutical Development: Investigated in research for potential therapeutic applications, including oxygen carriers and targeted drug delivery systems.
• Educational & Training Tools: Utilized in academic and laboratory training settings to teach principles of protein chemistry and clinical laboratory science.

Basic Information

Product Name	Hemoglobin Alberta
CAS No.	62493-89-4
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Alberta; Hemoglobin variant Alberta; Unstable hemoglobin Alberta; Hemoglobin α2β2 59 (E3) Lys→Glu; HBA2, HBB:c.179A>C; Hemoglobin A2 Alberta; Oxyhemoglobin Alberta; Methemoglobin Alberta
EINECS	Contact for details

Quality Control

Our Hemoglobin Alberta is produced and handled under stringent conditions to ensure batch-to-batch consistency and reliability for critical research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC, spectral analysis for correct heme environment, and verification of oxygen-binding characteristics. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be prepared with appropriate buffers and stored at 2-8°C for short-term use; avoid repeated freeze-thaw cycles. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance (Lyophilized)	Dark red to brown powder
Identification (IR / UV-Vis)	Conforms to standard for Hemoglobin Alberta
Purity (HPLC)	≥ 95% (by area)
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	< 5%
Solubility	Clear solution in phosphate buffer, pH 7.4
Oxygen Affinity (P50)	Contact for details
Bacterial Endotoxins	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.