Description

Benzyl 1-Hydroxy-2-Methylpropan-2-Ylcarbamate is a specialized carbamate derivative with a protected hydroxyl functionality, serving as a versatile synthetic intermediate in advanced organic synthesis. Its molecular structure makes it a valuable building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring carbamate or protected amino alcohol motifs.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and plant growth regulators where its structural features can impart specific biological activity.
• Peptide Mimetics & PROTACs: Serves as a precursor for constructing peptide-like molecules and proteolysis-targeting chimeras (PROTACs) in drug discovery.
• Polymer Chemistry: Acts as a monomer or chain transfer agent in the synthesis of specialized polyurethanes and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Benzyl 1-Hydroxy-2-Methylpropan-2-Ylcarbamate
CAS No.	62471-40-3
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	Benzyl (2-Hydroxy-1,1-dimethylethyl)carbamate; 2-[(Benzyloxycarbonyl)amino]-2-methylpropan-1-ol; 2-[(Cbz-Amino)-2-methyl]propan-1-ol; N-Cbz-2-Amino-2-methyl-1-propanol; Carbamic acid, N-(2-hydroxy-1,1-dimethylethyl)-, phenylmethyl ester; Z-2-Amino-2-methyl-1-propanol; Cbz-Amp-ol
EINECS	Contact for details

Quality Control

Our Benzyl 1-Hydroxy-2-Methylpropan-2-Ylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP for pharmaceutical intermediates and is compliant with REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.