Description

Methyl 3-(Trifluoromethyl)Phenylacetate is a high-purity organic ester compound, serving as a versatile and critical building block in advanced chemical synthesis. Its value lies in the unique trifluoromethylphenyl moiety, which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and reductions to construct complex molecular architectures in R&D and pilot-scale production.
• Flavor & Fragrance Chemistry: Utilized as an intermediate for creating sophisticated aromatic esters with unique olfactory profiles.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains, altering the surface properties and stability of specialty polymers.

Basic Information

Product Name	Methyl 3-(Trifluoromethyl)Phenylacetate
CAS No.	62451-84-7
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Methyl 2-[3-(Trifluoromethyl)phenyl]acetate; 3-(Trifluoromethyl)benzeneacetic Acid Methyl Ester; Methyl (3-Trifluoromethylphenyl)acetate; Methyl m-(Trifluoromethyl)phenylacetate; α-Toluenoic Acid, 3-(Trifluoromethyl)-, Methyl Ester; Methyl 3-(Trifluoromethyl)benzeneacetate; m-Trifluoromethylphenylacetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(Trifluoromethyl)Phenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.