Description

2-Bromo-3-(4-Methylphenyl)Propanenitrile is a versatile brominated aromatic nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive bromine atom and a nitrile group, makes it a valuable building block for constructing complex molecular architectures. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the bromine and nitrile functionalities enable specific modes of action.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic molecules used in electronic displays and optoelectronic devices.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce complex arylpropionitrile motifs.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new reaction pathways and novel heterocyclic compounds.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and other performance chemicals requiring tailored aromatic structures.

Basic Information

Product Name	2-Bromo-3-(4-Methylphenyl)Propanenitrile
CAS No.	62448-29-7
Molecular Formula	C10H10BrN
Molecular Weight	224.10 g/mol
Synonyms	2-Bromo-3-(p-tolyl)propanenitrile; 3-(4-Methylphenyl)-2-bromopropanenitrile; (2-Bromo-3-(4-methylphenyl)propionitrile; p-Methyl-α-bromohydrocinnamomitrile; 2-Bromo-3-(4-methylphenyl)propionitrile; α-Bromo-4-methylhydrocinnamomitrile; 62448-29-7; 2-Bromo-3-(p-tolyl)propionitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(4-Methylphenyl)Propanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.