Description

n-Hydroxy-2-Naphthylamine-n-Glucuronide is a conjugated metabolite formed from the glucuronidation of N-hydroxy-2-naphthylamine. This compound is of significant interest in biochemical and toxicological research, particularly in the study of aromatic amine metabolism and detoxification pathways. It serves as a critical reference standard and intermediate for researchers and manufacturers in the fields of analytical chemistry, pharmacology, and environmental safety testing.

Application

• Biochemical Research Standard: Used as a high-purity reference material for studying the metabolic fate and detoxification of aromatic amines like 2-naphthylamine.
• Analytical Method Development: Essential for calibrating and validating analytical methods (e.g., HPLC, LC-MS) in forensic, clinical, and environmental laboratories.
• Toxicology and Safety Assessment: Acts as a key metabolite in assays designed to understand carcinogenicity and the biotransformation pathways of industrial chemicals.
• Pharmaceutical Intermediate: Employed in the synthesis and development of specialized diagnostic agents or research compounds.
• Environmental Analysis: Used to trace and quantify exposure biomarkers in occupational health and environmental monitoring studies.

Basic Information

Product Name	n-Hydroxy-2-Naphthylamine-n-Glucuronide
CAS No.	62317-15-1
Molecular Formula	C₁₆H₁₇NO₇
Molecular Weight	335.31 g/mol
Synonyms	N-Hydroxy-2-naphthylamine glucuronide; 2-Naphthylhydroxylamine glucuronide; N-(2-Naphthyl)hydroxylamine-O-β-D-glucuronide; N-Hydroxy-β-naphthylamine glucuronide; 1-(β-D-Glucopyranosyluronic acid)-2-naphthylhydroxylamine; N-Hydroxy-2-NA glucuronide; Conjugate of N-hydroxy-2-naphthylamine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-2-Naphthylamine-n-Glucuronide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and analytical applications. Each lot is characterized using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term stability, consider storage under inert conditions if the material shows sensitivity to oxidation.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.