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Morphine 6-Acetate 3-Glucuronide CAS NO 62299-26-7


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CAS No.:62299-26-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Morphine 6-Acetate 3-Glucuronide is a key metabolite of morphine, formed via glucuronidation and acetylation, which is critical for pharmacological and toxicological studies. This compound is essential for researchers and manufacturers developing analytical methods, conducting metabolism studies, and ensuring drug safety and compliance. It is primarily used in pharmaceutical R&D, forensic toxicology, and as a certified reference material for high-performance liquid chromatography (HPLC) and mass spectrometry (MS) applications.

Application

  • Pharmaceutical Reference Standard: Serves as a certified metabolite standard for the quantification of morphine and its derivatives in drug development and bioanalysis.
  • Metabolism and Pharmacokinetic Studies: Used to investigate the metabolic pathways, bioavailability, and clearance rates of morphine in preclinical and clinical research.
  • Forensic Toxicology: Employed as a calibrator or control in analytical assays to detect and confirm opioid use in forensic and workplace drug testing.
  • Biomarker Research: Acts as a specific biomarker in studies examining opioid exposure, addiction mechanisms, and patient monitoring.
  • Quality Control (QC) Testing: Utilized by pharmaceutical manufacturers to validate analytical methods and ensure the purity and consistency of opioid-based medications.
  • Academic Research: Applied in university and institutional labs for studies on pain management, neuropharmacology, and glucuronidation enzyme activity.

Basic Information

Product Name Morphine 6-Acetate 3-Glucuronide
CAS No. 62299-26-7
Molecular Formula C25H29NO11
Molecular Weight 519.50 g/mol
Synonyms Morphine-6-acetate-3-β-D-glucuronide; 3-Glucuronosyl-6-acetylmorphine; Morphine 3-β-D-Glucuronide 6-acetate; 6-Acetylmorphine 3-glucuronide; 6-Monoacetylmorphine-3-glucuronide; M6G3G; M-6-A-3-G
EINECS Contact for details

Quality Control

Our Morphine 6-Acetate 3-Glucuronide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and reference material use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants and inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥95.0%
Purity (HPLC) ≥98.0%
Water Content ≤2.0%
Residue on Ignition ≤0.5%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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