Description

1,2:5,6-Di-o-Cyclohexylidene-3-Cyano-α-D-Allofuranose is a high-purity, protected carbohydrate derivative, specifically a cyano-substituted allofuranose with dual cyclohexylidene protecting groups. This compound is a critical chiral intermediate and building block in sophisticated organic synthesis, valued for its defined stereochemistry and functional handles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Antiviral Drug Development: Serves as a precursor in the construction of sugar moieties for potential therapeutic agents targeting viruses like HIV, hepatitis, and herpes.
• Carbohydrate Chemistry Research: Used as a protected sugar derivative to study glycosylation reactions, conformational analysis, and to synthesize complex oligosaccharides.
• Chemical Biology Probes: Employed in the creation of labeled or modified sugars for investigating biological pathways and enzyme mechanisms.
• Asymmetric Synthesis: Acts as a chiral pool starting material or auxiliary for the stereoselective construction of other complex organic molecules.
• Process Chemistry & Scale-up: Suitable for development into a registered starting material (RSM) for cGMP manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1,2:5,6-Di-o-Cyclohexylidene-3-Cyano-α-D-Allofuranose
CAS No.	62293-19-0
Molecular Formula	C19H27NO5
Molecular Weight	349.42 g/mol
Synonyms	3-Cyano-1,2:5,6-di-O-cyclohexylidene-α-D-allofuranose; 3-Cyano-1,2:5,6-di-O-cyclohexylidene-α-D-allose; 1,2:5,6-Di-O-cyclohexylidene-3-cyano-α-D-allofuranose; α-D-Allofuranose, 3-cyano-1,2:5,6-di-O-cyclohexylidene-; 3-Cyano-1,2:5,6-di-O-cyclohexylidene-α-D-allofuranose; Protected 3-Cyano Allofuranose; D-Allose derivative, 3-cyano-1,2:5,6-di-O-cyclohexylidene-
EINECS	Contact for details

Quality Control

Our 1,2:5,6-Di-o-Cyclohexylidene-3-Cyano-α-D-Allofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.