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Epidermal Growth Factor CAS NO 62253-63-8
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CAS No.:62253-63-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Epidermal Growth Factor (EGF) is a potent, single-chain polypeptide that plays a critical role in cellular proliferation, differentiation, and survival. Its primary commercial value lies in its ability to stimulate skin cell regeneration and wound healing, making it a highly sought-after active ingredient. This product is essential for manufacturers in the cosmeceutical, biomedical research, and advanced wound care sectors seeking to develop high-performance formulations.
Application
- Cosmeceutical Formulations: Key active in anti-aging serums, creams, and masks to promote collagen synthesis and reduce the appearance of fine lines and wrinkles.
- Biomedical & Cell Culture Research: Used as a supplement in cell culture media to stimulate the growth of epidermal and epithelial cells.
- Advanced Wound Healing: Incorporated into gels, sprays, and dressings to accelerate tissue repair in diabetic ulcers, burns, and surgical wounds.
- Hair Growth Solutions: Component in topical treatments and scalp serums aimed at revitalizing hair follicles and promoting hair growth.
- Ophthalmic Preparations: Used in formulations for corneal injury repair and dry eye syndrome treatments.
- Bio-engineering & 3D Tissue Culture: Essential growth factor for constructing skin models and other epithelial tissues in vitro.
Basic Information
| Product Name | Epidermal Growth Factor |
| CAS No. | 62253-63-8 |
| Molecular Formula | C726H1171N203O223S6 |
| Molecular Weight | Approx. 6,200 Da |
| Synonyms | EGF; Urogastrone; β-Urogastrone; Human Epidermal Growth Factor; hEGF; Epidermal Growth Factor, Human; CAS 62253-63-8; Recombinant Human Epidermal Growth Factor (rhEGF) |
| EINECS | Contact for details |
Quality Control
Our Epidermal Growth Factor is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to a comprehensive battery of tests including HPLC for purity, SDS-PAGE for homogeneity, mass spectrometry for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing potency (ED50), purity, and sterility are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC/MS) | Conforms to standard |
| Purity (HPLC) | ≥ 95.0% |
| Molecular Weight | 6.0 - 6.4 kDa (SDS-PAGE) |
| Biological Activity (ED50) | ≤ 1.0 ng/ml |
| Endotoxin | < 1.0 EU/μg |
| Solubility | Soluble in water or PBS (pH 7.2-7.4) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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