Description

Moricizine Sulfoxide CAS NO 62152-17-4 is a key pharmaceutical intermediate and metabolite of the antiarrhythmic agent Moricizine. This compound is of significant importance for research and development in cardiovascular pharmacology, serving as a critical reference standard for metabolic studies and analytical method validation. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in drug development, quality control, and regulatory compliance activities.

Application

• Primary reference standard for the quantification of Moricizine and its metabolites in pharmacokinetic and bioanalytical studies.
• Critical intermediate in the research-scale synthesis and process development of Moricizine hydrochloride.
• Used in impurity profiling and method development for the quality control of Moricizine active pharmaceutical ingredients (APIs).
• Essential material for conducting stability studies and forced degradation studies of Moricizine formulations.
• Valuable tool for academic and industrial research into the metabolism, mechanism of action, and structure-activity relationships of class I antiarrhythmic drugs.
• Applied in the development and calibration of analytical instrumentation, including High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) systems.

Basic Information

Product Name	Moricizine Sulfoxide
CAS No.	62152-17-4
Molecular Formula	C22H25N3O4S
Molecular Weight	427.52 g/mol
Synonyms	Ethmozine Sulfoxide; 10-(3-Morpholinopropionyl)phenothiazine 5-Oxide; Phenothiazine, 10-[3-(4-morpholinyl)-1-oxopropyl]-, 5-oxide; Moricizine Sulfoxide Metabolite; Moricizine S-Oxide
EINECS	Contact for details

Quality Control

Our Moricizine Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical reference standards. Certificates of Analysis (COA) detailing specific results for assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.