Description

(S)-n-Boc-4-Bromophenylalanine is a high-purity, non-natural amino acid derivative featuring a chiral center and a brominated aromatic side chain. This compound is a critical chiral building block in modern pharmaceutical research and development, enabling the synthesis of complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a bromophenylalanine residue, allowing for further functionalization via cross-coupling reactions.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of potent protease inhibitors.
• Chemical Biology & Proteomics: Employed in the creation of activity-based probes and affinity tags for studying protein function and interactions.
• Material Science Research: Used to synthesize novel chiral polymers and advanced organic materials with specific optical properties.

Basic Information

Product Name	(S)-n-Boc-4-Bromophenylalanine
CAS No.	62129-39-9
Molecular Formula	C₁₄H₁₈BrNO₄
Molecular Weight	344.20 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-bromophenyl)propanoic acid; Boc-4-Bromo-DL-phenylalanine; Boc-(S)-4-Bromophenylalanine; N-Boc-4-bromo-L-phenylalanine; tert-Butyl (S)-(4-bromophenyl)alaninate; (S)-3-(4-Bromophenyl)-2-[(tert-butoxycarbonyl)amino]propanoic acid; BOC-4-Br-Phe-OH; (S)-N-(tert-Butoxycarbonyl)-4-bromophenylalanine
EINECS	Contact for details

Quality Control

Our (S)-n-Boc-4-Bromophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.