Description

Dnp Maleimide is a specialized chemical reagent featuring a maleimide group activated with a 2,4-dinitrophenyl (Dnp) moiety. This compound is critical for researchers and manufacturers requiring precise bioconjugation and protein modification capabilities. It is primarily utilized in the development of biochemical probes, antibody-drug conjugates (ADCs), and advanced material science applications. The product is supplied under stringent quality control to ensure reliability for sensitive research and production processes.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, peptides, and antibodies via thiol-maleimide chemistry.
• Antibody-Drug Conjugate (ADC) Linker Precursor: Serves as a key intermediate in the synthesis of cleavable linkers for targeted cancer therapies.
• Polymer Modification: Used to functionalize polymers and hydrogels to introduce reactive handles or specific ligands.
• Surface Immobilization: Enables the covalent attachment of biomolecules to sensor chips, nanoparticles, and other solid supports.
• Proteomics Research: Acts as a tool for studying protein structure, interactions, and activity through selective modification.
• Crosslinking Agent: Facilitates the formation of stable crosslinks between thiol-containing molecules in material and biochemical systems.

Basic Information

Product Name	Dnp Maleimide
CAS No.	62024-74-2
Molecular Formula	C13H9N3O6
Molecular Weight	303.23 g/mol
Synonyms	N-(2,4-Dinitrophenyl)maleimide; 1-(2,4-Dinitrophenyl)-1H-pyrrole-2,5-dione; Maleimide, N-(2,4-dinitrophenyl)-; DNP-Maleimide; 2,4-Dinitrophenylmaleimide; Dnp-Mal; DNP-MI
EINECS	Contact for details

Quality Control

Our Dnp Maleimide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.