Description

(12R,15S)-12,15-Epoxy-15,20-Dihydro-16A-Homo-21-Norsenecionan-11,16A-Dione is a high-purity, complex organic compound belonging to the class of modified senecionan alkaloids. This specialized intermediate is valued for its unique stereochemistry and functional groups, which make it a critical building block in advanced synthetic chemistry. It is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel bioactive molecules and for use in complex total synthesis projects.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Organic Synthesis Research: Used as a sophisticated building block in academic and industrial laboratories for methodological studies in stereoselective synthesis and natural product analog creation.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry: Provides a structurally complex scaffold for structure-activity relationship (SAR) studies and the discovery of new lead compounds with potential therapeutic activity.

Basic Information

Product Name	(12R,15S)-12,15-Epoxy-15,20-Dihydro-16A-Homo-21-Norsenecionan-11,16A-Dione
CAS No.	62018-78-4
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	(12R,15S)-12,15-Epoxy-15,20-dihydro-16a-homo-21-norsenecionan-11,16a-dione; 16a-Homo-21-norsenecionan-11,16a-dione, 12,15-epoxy-15,20-dihydro-, (12R,15S)-; 12,15-Epoxy-15,20-dihydro-16a-homo-21-norsenecionan-11,16a-dione; Modified Senecionine Derivative; Homo-norsenecionan Dione Epoxide
EINECS	Contact for details

Quality Control

Every batch of (12R,15S)-12,15-Epoxy-15,20-Dihydro-16A-Homo-21-Norsenecionan-11,16A-Dione is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.