Description

2-(3-Fluorophenyl)Morpholine is a high-purity fluorinated morpholine derivative, a key building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for creating complex molecules with tailored properties for demanding applications. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate a fluorinated aromatic morpholine moiety.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Acts as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where the morpholine ring contributes to specific material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories engaged in novel compound discovery.

Basic Information

Product Name	2-(3-Fluorophenyl)Morpholine
CAS No.	62008-55-3
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-Fluoro-2-morpholinobenzene; 2-Morpholino-3-fluorobenzene; 3-Fluorophenylmorpholine; 2-(3-Fluorophenyl)-1,4-oxazinane; 2-(3-Fluorophenyl)-4-morpholine; 3-Fluoro-2-(4-morpholinyl)benzene; 2-(m-Fluorophenyl)morpholine
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.