Description

Acetamide, 2,2,2-Trifluoro-n-(2-Fluorophenyl)- is a specialized fluorinated acetamide derivative, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring both trifluoromethyl and fluorophenyl groups, makes it a critical building block for introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical design. This compound is essential for research and development chemists and process engineers in the life sciences sector seeking to enhance the metabolic stability, bioavailability, and binding affinity of novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers and liquid crystals with unique optical or electronic properties.
• Fluorination Chemistry: Employed as a reagent in medicinal chemistry for late-stage fluorination, a pivotal step in optimizing drug candidate profiles.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical laboratories.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Fluorophenyl)-
CAS No.	61984-68-7
Molecular Formula	C9H7F4NO
Molecular Weight	221.15 g/mol
Synonyms	N-(2-Fluorophenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-fluorophenyl)acetamide; 2-Fluorophenyltrifluoroacetamide; α,α,α-Trifluoro-2'-fluoroacetanilide; TFAA-2F; 2-Fluoroaniline, N-(trifluoroacetyl)-; Trifluoroacetic acid 2-fluoroanilide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2-Fluorophenyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available upon request, ensuring compliance with the rigorous standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.