Description

n-Benzoyl-D-Glucosamine CAS NO 61949-16-4 is a chemically modified derivative of D-glucosamine, where the amino group is protected by a benzoyl moiety. This modification enhances its stability and makes it a valuable key chiral intermediate and building block in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of glycosidase inhibitors, antiviral agents, and other bioactive molecules.
• Glycobiology Research: Used as a substrate or inhibitor in enzymatic studies to investigate carbohydrate metabolism and cell signaling pathways.
• Chiral Synthesis: Acts as a versatile chiral pool starting material for the asymmetric synthesis of complex natural products and drug candidates.
• Bioconjugate Chemistry: Employed in the development of glycoconjugates, including glycoproteins and glycolipids, for diagnostic and therapeutic applications.
• Cosmetic Actives R&D: Investigated for potential use in advanced skincare formulations targeting skin barrier function and hydration.
• Chemical Biology Probes: Utilized to create labeled analogs for studying protein-carbohydrate interactions and cellular uptake mechanisms.

Basic Information

Product Name	n-Benzoyl-D-Glucosamine
CAS No.	61949-16-4
Molecular Formula	C₁₃H₁₇NO₆
Molecular Weight	283.28 g/mol
Synonyms	N-Benzoyl-D-glucosamine; 2-Amino-2-deoxy-D-glucopyranose N-benzoate; D-Glucosamine, N-benzoyl-; 1,3,4,6-Tetra-O-acetyl-2-benzamido-2-deoxy-β-D-glucopyranose (precursor); Benzoylglucosamine; N-(Benzoyl)-D-glucosamine; 2-Benzamido-2-deoxy-D-glucose
EINECS	Contact for details

Quality Control

Our n-Benzoyl-D-Glucosamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+40° to +50° (c=1 in H₂O)
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.