Description

[Ethyl[(S)-1-Phenylethyl]Amino]Diphenylphosphine CAS NO 61937-85-7 is a chiral, non-racemic organophosphorus compound featuring a stereogenic phosphorus center and a chiral amine auxiliary. This compound matters as a highly valuable ligand precursor and chiral auxiliary in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel catalytic processes and chiral building blocks.

Application

• Asymmetric Catalysis: As a precursor for chiral phosphine ligands used in transition metal-catalyzed reactions like hydrogenation, cross-coupling, and hydroformylation.
• Pharmaceutical Intermediate Synthesis: For the stereoselective construction of complex molecules, including active pharmaceutical ingredients (APIs) with defined chirality.
• Agrochemical Research: In the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: As a building block for chiral polymers or as a modifier for surfaces in sensor technology.
• Academic & Industrial R&D: A key reagent for methodological development in organic and organometallic chemistry.
• Ligand Library Development: For creating diverse chiral ligand libraries for high-throughput screening in catalyst discovery.

Basic Information

Product Name	[Ethyl[(S)-1-Phenylethyl]Amino]Diphenylphosphine
CAS No.	61937-85-7
Molecular Formula	C22H24NP
Molecular Weight	333.41 g/mol
Synonyms	(S)-(-)-[Ethyl(1-phenylethyl)amino]diphenylphosphine; (S)-N-Ethyl-α-methylbenzylamino-diphenylphosphine; (S)-(-)-N-Ethyl-1-phenylethylaminodiphenylphosphine; (S)-P,P-Diphenyl-N-ethyl-N-(1-phenylethyl)phosphinous amide; (S)-EAPDP; Chiral EAPDP Ligand Precursor; (S)-EAPA-Phos; (S)-N-Ethyl-N-(1-phenylethyl)-P,P-diphenylphosphinous amide
EINECS	Contact for details

Quality Control

Our [Ethyl[(S)-1-Phenylethyl]Amino]Diphenylphosphine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and moisture-sensitive; ensure the container is sealed tightly after each use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.