Description

Boc-S-(4-Methylbenzyl)-L-Cysteine is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals and bioactive peptides. It is particularly valuable in solid-phase peptide synthesis (SPPS) for introducing the cysteine residue with a thiol-protecting group that is stable to acidic conditions but readily removable. Industries such as pharmaceutical R&D, biotechnology, and fine chemical production rely on this reagent for constructing complex peptide structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate protected cysteine residues.
• Bioconjugation Chemistry: Serves as a starting material for creating linkers or modifying biomolecules via its protected thiol group.
• Research & Development: Employed in academic and industrial labs for exploring new peptide sequences and their biological functions.
• Production of Custom Peptides: Essential for contract manufacturing organizations (CMOs) producing therapeutic or diagnostic peptides for clients.

Basic Information

Product Name	Boc-S-(4-Methylbenzyl)-L-Cysteine
CAS No.	61925-77-7
Molecular Formula	C₁₆H₂₃NO₄S
Molecular Weight	325.42 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-(4-methylbenzyl)-L-cysteine; Boc-Cys(4-MeBzl)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-((4-methylbenzyl)thio)propanoic acid; Boc-S-p-Methylbenzyl-L-cysteine; N-Boc-S-(p-Methylbenzyl)-L-cysteine; Boc-L-Cysteine(S-4-methylbenzyl); tert-Butyloxycarbonyl-S-(4-methylbenzyl)-L-cysteine
EINECS	Contact for details

Quality Control

Our Boc-S-(4-Methylbenzyl)-L-Cysteine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical research and cGMP-compliant applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); therefore, it should be handled in a dry environment and the container kept sealed when not in use. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.