Description

Pepsinogen C is a zymogen, or inactive precursor, to the digestive enzyme pepsin, which is crucial for protein breakdown in the stomach. This high-purity biochemical is essential for research, diagnostic applications, and the development of enzyme-based products. It is primarily utilized by the pharmaceutical, biotechnology, and in-vitro diagnostics industries for its role in studying gastric physiology and related pathologies.

Application

• Biochemical Research: Used as a critical substrate and model protein in studies of enzyme kinetics, activation mechanisms, and protein structure-function relationships.
• In-Vitro Diagnostics (IVD): Serves as a key antigen or calibrator in immunoassays and test kits for measuring pepsinogen levels, aiding in the assessment of gastric mucosa function and screening for atrophic gastritis.
• Pharmaceutical Development: Employed in the research and quality control of digestive enzyme supplements and therapeutic agents targeting gastric disorders.
• Enzyme Production: Acts as a starting material for the controlled generation of active pepsin under specific acidic conditions for various industrial enzymatic processes.
• Cell Culture & Biotechnology: Utilized in specialized cell culture media and bioprocessing research where precise enzymatic activity is required.

Basic Information

Product Name	Pepsinogen C
CAS No.	61536-72-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Progastricsin; Pepsinogen II; Pepsinogen 5, group I (pepsinogen A); Gastricsin precursor; Pepsinogen group II; PGA5; PGC
EINECS	Contact for details

Quality Control

Our Pepsinogen C is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and activity meet the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), biological activity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content (Biuret)	≥ 90.0%
Specific Activity	Contact for details
Moisture (KF)	≤ 5.0%
Solubility	Soluble in water or appropriate buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.