Description

2-(2,5-Dioxotetrahydro-1H-Pyrrol-1-Yl)Acetonitrile is a versatile heterocyclic building block featuring a reactive maleimide moiety and a nitrile group. This compound is essential for advanced organic synthesis, enabling the creation of complex molecules through selective conjugation and cycloaddition reactions. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted drug delivery systems and bioconjugates.
• Bioconjugation Reagent: Used to functionalize proteins, peptides, and antibodies via thiol-maleimide "click" chemistry for diagnostic and therapeutic applications.
• Polymer Chemistry: Serves as a cross-linking agent or monomer for producing specialty polymers with tailored thermal and mechanical properties.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the surface modification of nanomaterials and the creation of functional coatings and adhesives.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and creating molecular libraries.

Basic Information

Product Name	2-(2,5-Dioxotetrahydro-1H-Pyrrol-1-Yl)Acetonitrile
CAS No.	61516-81-2
Molecular Formula	C6H6N2O2
Molecular Weight	138.12 g/mol
Synonyms	1-Maleimidoacetonitrile; N-(Cyanomethyl)maleimide; 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetonitrile; Maleimidomethyl cyanide; 1-(Cyanomethyl)-1H-pyrrole-2,5-dione; 2-(2,5-Dioxopyrrolidin-1-yl)acetonitrile; N-Maleoylglycinonitrile; Acetonitrile, (2,5-dioxo-1-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dioxotetrahydro-1H-Pyrrol-1-Yl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.