Description

(9H-Fluoren-9-Yl)Methyl (Pyrrolidin-2-Ylmethyl)Carbamate Hydrochloride is a specialized, high-purity chemical building block primarily used in advanced organic synthesis. This compound is valued for its role as a protected amine intermediate, enabling the controlled construction of complex molecules in sensitive applications. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers working on peptide mimetics, drug discovery, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a building block for introducing pyrrolidine-based structures.
• Protecting Group Strategy: The Fmoc (9-fluorenylmethoxycarbonyl) group provides a base-labile protecting group for amines, critical for orthogonal synthesis.
• Medicinal Chemistry Research: Serves as a scaffold or intermediate in the design and synthesis of libraries for high-throughput screening.
• Bioconjugation: Can be utilized in the preparation of labeled probes or conjugates for biochemical studies.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals requiring precise molecular architecture.

Basic Information

Item	Details
Product Name	(9H-Fluoren-9-Yl)Methyl (Pyrrolidin-2-Ylmethyl)Carbamate Hydrochloride
CAS No.	61502-90-7
Molecular Formula	C21H24N2O2 • HCl
Molecular Weight	372.89 g/mol
Synonyms	Fmoc-Pyrrolidin-2-Ylmethylamine Hydrochloride; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolinamide Hydrochloride; (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxamide Hydrochloride; Fmoc-Pro-NH2•HCl; Nα-Fmoc-L-prolinamide hydrochloride; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolinamide hydrochloride; (S)-1-((((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl (Pyrrolidin-2-Ylmethyl)Carbamate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.