Description

2-Amino-4-Trifluoromethyl-Benzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its trifluoromethyl group, which imparts unique physicochemical properties to target molecules, enhancing their metabolic stability and lipophilicity. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), especially in the development of drugs targeting the central nervous system, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Material Science: Employed in creating specialty polymers and coatings with enhanced chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new fluorination chemistry and creating novel molecular libraries.

Basic Information

Product Name	2-Amino-4-Trifluoromethyl-Benzoic Acid Methyl Ester
CAS No.	61500-87-6
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	Methyl 2-amino-4-(trifluoromethyl)benzoate; 2-Amino-α,α,α-trifluoro-p-toluic acid methyl ester; Benzoic acid, 2-amino-4-(trifluoromethyl)-, methyl ester; Methyl 2-amino-α,α,α-trifluoro-p-toluate; 4-(Trifluoromethyl)anthranilic acid methyl ester; 2-Amino-4-trifluoromethylbenzoic acid methyl ester; Methyl 4-(trifluoromethyl)anthranilate
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Trifluoromethyl-Benzoic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.