Description

(2S,4S)-4-Diphenylphosphino 2-Diphenylphosphinomethyl Pyrrolidine is a high-value, chiral bidentate phosphine ligand widely used in asymmetric catalysis. Its precise stereochemistry and robust coordination properties make it a critical component for achieving high enantioselectivity in various transition metal-catalyzed reactions. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop efficient and selective synthetic routes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure pharmaceutical intermediates.
• Catalyst component for asymmetric C-C bond-forming reactions, including cross-coupling and allylic alkylation.
• Key reagent in the development of stereoselective synthesis processes for active pharmaceutical ingredients (APIs).
• Used in academic and industrial research to explore new catalytic methodologies and optimize existing ones.
• Employed in the synthesis of agrochemicals and flavors & fragrances where chiral purity is required.
• Facilitates process chemistry scale-up from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(2S,4S)-4-Diphenylphosphino 2-Diphenylphosphinomethyl Pyrrolidine
CAS No.	61478-29-3
Molecular Formula	C29H30NP2
Molecular Weight	457.50 g/mol
Synonyms	(2S,4S)-(-)-2,4-Bis(diphenylphosphino)methylpyrrolidine; (S,S)-PPM; (2S,4S)-PPM; (2S,4S)-2,4-Bis(diphenylphosphinomethyl)pyrrolidine; (S,S)-2,4-Bis(diphenylphosphinomethyl)pyrrolidine; (S,S)-BDPP; PPM Ligand; SK-CC01-A
EINECS	Contact for details

Quality Control

Our production of (2S,4S)-4-Diphenylphosphino 2-Diphenylphosphinomethyl Pyrrolidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. All materials are characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and prolong shelf-life. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.