Description

H-Ala-Ala-Pro-Ala-Ala-Oh is a high-purity, synthetic pentapeptide sequence featuring a central proline residue. This specific oligopeptide is valued for its role as a critical building block and model substrate in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of protease enzyme studies, peptide-based drug discovery, and the synthesis of more complex bioactive compounds.

Application

• Biochemical Research: Used as a specific substrate for studying the activity, kinetics, and inhibition of proteolytic enzymes, particularly those cleaving at proline residues.
• Pharmaceutical Intermediates: Serves as a key fragment in the solid-phase or solution-phase synthesis of longer therapeutic peptides and peptidomimetics.
• Enzyme Characterization: Employed in assay development for high-throughput screening (HTS) to identify novel enzyme inhibitors or activators.
• Academic & Industrial R&D: Provides a standardized reference compound for method validation and quality control in peptide analysis laboratories.
• Nutritional Science Studies: Can be utilized in research investigating collagen-derived peptide absorption and bioavailability.

Basic Information

Product Name	H-Ala-Ala-Pro-Ala-Ala-Oh
CAS No.	61430-17-9
Molecular Formula	C20H32N6O7
Molecular Weight	468.51 g/mol
Synonyms	Ala-Ala-Pro-Ala-Ala; AAPA; L-Alanyl-L-alanyl-L-prolyl-L-alanyl-L-alanine; Pentapeptide A-A-P-A-A; H-Ala-Ala-Pro-Ala-Ala-OH; AAPAA; Proline-containing pentapeptide; 61430-17-9 (CAS)
EINECS	Contact for details

Quality Control

Every batch of our H-Ala-Ala-Pro-Ala-Ala-Oh is manufactured under strict quality management systems. We guarantee high purity and consistency through comprehensive analytical testing, including HPLC, MS, and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and absence of specific impurities. Our quality commitment ensures the material meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.