Description

2-Chloro-4-Fluorophenacyl Bromide is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its reactive bromoacetyl and halogenated aromatic structure makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and pesticides, leveraging its halogenated phenacyl structure.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other performance chemicals requiring specific halogenated motifs.
• Academic and R&D Laboratories: Essential reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.
• Material Science Research: Potential monomer or modifier in the development of specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	2-Chloro-4-Fluorophenacyl Bromide
CAS No.	61397-54-4
Molecular Formula	C8H5BrClFO
Molecular Weight	251.48 g/mol
Synonyms	2-Bromo-1-(2-chloro-4-fluorophenyl)ethan-1-one; 2-Bromo-2'-chloro-4'-fluoroacetophenone; α-Bromo-2-chloro-4-fluoroacetophenone; 1-(2-Chloro-4-fluorophenyl)-2-bromoethanone; Phenacyl bromide, 2-chloro-4-fluoro-; 2-Chloro-4-fluorophenacylbromide; 2-Chloro-4-fluoro-ω-bromoacetophenone; 2'-Chloro-4'-fluorophenacyl bromide
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorophenacyl Bromide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.