Description

2'-Ethoxyuridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of novel antiviral and anticancer agents, where structural modifications can enhance therapeutic efficacy and selectivity. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs. The material is supplied with a focus on high purity and consistency to meet the stringent requirements of advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating nucleoside metabolism, enzyme inhibition, and structure-activity relationships (SAR).
• Pro-drug Development: Serves as a precursor molecule for designing pro-drugs with improved bioavailability and targeted delivery.
• Antiviral Agent Synthesis: Incorporated into the synthetic pathways for potential therapeutics targeting viral polymerases.
• Labeled Compound Synthesis: Acts as a starting material for preparing isotopically labeled (e.g., 13C, 15N) nucleosides for metabolic tracing studies.
• Oligonucleotide Chemistry: Can be used in the solid-phase synthesis of modified oligonucleotides for diagnostic or therapeutic applications.

Basic Information

Product Name	2'-Ethoxyuridine
CAS No.	61373-43-1
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	2'-O-Ethyluridine; 1-[(2R,3R,4R,5R)-3-Ethoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; Uridine, 2'-O-ethyl-; 2'-Ethoxy-1-β-D-ribofuranosyluracil; 2'-Ethoxyuridine; 2'-O-Ethyl-uridine
EINECS	Contact for details

Quality Control

Our 2'-Ethoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are designed to meet the high standards of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.