Description

Flumezapine is a high-purity chemical compound of significant interest in advanced research and development. This specialized material serves as a critical intermediate or reference standard in the synthesis of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in neuroscience and CNS drug discovery programs. The compound's specific properties make it valuable for investigative studies requiring precise chemical building blocks.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis pathway for novel therapeutic agents targeting the central nervous system.
• Reference Standard: Used as a high-purity analytical standard in method development and quality control for related active pharmaceutical ingredients (APIs).
• Neuroscience Studies: Employed in preclinical research to investigate structure-activity relationships (SAR) and receptor binding profiles.
• Chemical Synthesis: Acts as a specialized building block for medicinal chemists creating libraries of compounds for biological screening.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic chemistry and pharmacology.

Basic Information

Product Name	Flumezapine
CAS No.	61325-80-2
Molecular Formula	C₁₉H₂₀FN₃O
Molecular Weight	325.38 g/mol
Synonyms	8-Fluoro-6-(4-methylpiperazin-1-yl)-11H-benzo[b]euro[2,3-e][1,4]diazepine; Flumezapin; Flumezepine; CRM-610; Compound 610
EINECS	Contact for details

Quality Control

Our Flumezapine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation via IR and MS. A detailed Certificate of Analysis (COA) is provided with each batch, confirming compliance with agreed specifications. We support research and development with materials produced to meet the stringent requirements of cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.