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Dl-Norleucine, Ethyl Ester, Hydrochloride CAS NO 61299-11-4


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CAS No.:61299-11-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dl-Norleucine, Ethyl Ester, Hydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of norleucine, a non-proteinogenic amino acid. This compound is a crucial building block in organic synthesis and peptide chemistry, offering a stable, activated form for controlled coupling reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing novel compounds and active ingredients.

Application

  • Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of new drug candidates and active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis to incorporate the norleucine residue.
  • Biochemical Research: Employed in metabolic studies and as a non-natural amino acid analog in protein engineering and structure-activity relationship (SAR) studies.
  • Agrochemical Development: Acts as an intermediate in the synthesis of novel pesticides, herbicides, and plant growth regulators.
  • Fine Chemical Synthesis: Utilized in the preparation of complex organic molecules, including dyes, flavors, and fragrances.

Basic Information

Product Name Dl-Norleucine, Ethyl Ester, Hydrochloride
CAS No. 61299-11-4
Molecular Formula C8H18ClNO2
Molecular Weight 195.69 g/mol
Synonyms DL-2-Aminohexanoic Acid Ethyl Ester Hydrochloride; Ethyl DL-Norleucinate Hydrochloride; Norleucine Ethyl Ester HCl; (±)-2-Aminohexanoic Acid Ethyl Ester Hydrochloride; H-DL-Nle-OEt·HCl; Ethyl DL-α-Aminocaproate Hydrochloride; DL-Norleucine Ethyl Ester Hydrochloride
EINECS Contact for details

Quality Control

Our Dl-Norleucine, Ethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, optical purity (where applicable), and impurity profiles. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Melting Point Contact for details
Loss on Drying ≤1.0%
Heavy Metals ≤20 ppm
Residue on Ignition ≤0.1%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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