Description

Thromboxane-A Synthase CAS NO 61276-89-9 is a critical enzyme involved in the arachidonic acid cascade, specifically catalyzing the conversion of prostaglandin H2 to thromboxane A2. This compound is essential for researchers and pharmaceutical developers studying cardiovascular physiology, platelet aggregation, and inflammatory pathways. It is primarily utilized in biochemical research, drug discovery programs, and the development of diagnostic assays targeting thrombotic disorders.

Application

• Biochemical Research: Used as a key reagent to study the thromboxane pathway, enzyme kinetics, and inhibitor screening.
• Pharmaceutical R&D: Critical for the discovery and validation of novel antiplatelet and antithrombotic drug candidates.
• Diagnostic Development: Employed in the development of enzyme-linked immunosorbent assays (ELISAs) and other diagnostic kits for cardiovascular risk assessment.
• Academic Studies: Supports fundamental research in physiology, pharmacology, and pathology related to hemostasis and inflammation.
• Enzyme Characterization: Used to investigate enzyme structure, function, and regulatory mechanisms in vitro.

Basic Information

Product Name	Thromboxane-A Synthase
CAS No.	61276-89-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Thromboxane Synthase; Thromboxane A Synthase; TXAS; TXA2 Synthase; CYP5A1; Cytochrome P450 5A1; Prostaglandin H2 Thromboxane-A Isomerase; Thromboxane Synthetase
EINECS	Contact for details

Quality Control

Our Thromboxane-A Synthase is produced and handled under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous purity and activity assays. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity level, and stability data is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain activity. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Purity (SDS-PAGE)	> 90%
Specific Activity	Contact for details
Protein Concentration	Contact for details
Buffer Composition	Specified on COA
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.