Description

Cefonicid CAS NO 61270-58-4 is a second-generation cephalosporin antibiotic known for its broad-spectrum activity against Gram-positive and Gram-negative bacteria. It is valued for its extended half-life and stability, making it a critical intermediate in the synthesis of finished pharmaceutical dosage forms. This compound is essential for manufacturers in the pharmaceutical and biotechnology sectors developing injectable antibiotic formulations for serious infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical ingredient in the manufacture of injectable antibiotic formulations.
• Antibiotic Synthesis Intermediate: Serves as a key intermediate in the synthesis of more complex cephalosporin derivatives and prodrugs.
• Research & Development: Used in microbiological and pharmacological research to study bacterial resistance mechanisms and develop new antimicrobial agents.
• Veterinary Medicine: Employed in the development of antibiotic treatments for bacterial infections in animals.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or microbiological assay calibration.

Basic Information

Item	Details
Product Name	Cefonicid
CAS No.	61270-58-4
Molecular Formula	C18H18N6O8S2
Molecular Weight	510.50 g/mol
Synonyms	Cefonicid; Cefonicid Sodium; SK&F 75073; Monocid; 7-[[(Hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R,7R)-7-[(R)-2-Hydroxy-2-phenylacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Cefonicid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
pH (1% aqueous solution)	4.5 - 6.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.