Description

Capsaicin Impurity 2 CAS NO 61229-07-0 is a high-purity chemical reference standard used for analytical and research purposes. This compound is critically important for ensuring the quality, safety, and regulatory compliance of capsaicin and related capsaicinoid products. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) for use in method development, validation, and impurity profiling.

Application

• Pharmaceutical Impurity Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of impurities in capsaicin API batches during quality control (QC).
• Analytical Method Development & Validation: Essential for developing and validating HPLC, UPLC, or GC methods to ensure accurate impurity detection and separation.
• Stability Studies: Employed to monitor the formation of degradation products in capsaicin formulations under various stress conditions.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., for FDA, EMA) by providing a characterized impurity for inclusion in drug master files (DMFs).
• Research on Capsaicinoid Chemistry: Serves as a key intermediate or analog in academic and industrial research studying the structure-activity relationships of vanilloid receptor agonists.
• Quality Assurance in Nutraceuticals: Used to assess purity and authenticity in high-value capsaicin-based dietary supplements and topical preparations.

Basic Information

Item	Detail
Product Name	Capsaicin Impurity 2
CAS No.	61229-07-0
Molecular Formula	C18H27NO3
Molecular Weight	305.41 g/mol
Synonyms	8-Methyl-N-vanillyl-trans-6-nonenamide; Dihydrocapsaicin Impurity; (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; Capsaicin Related Compound; trans-8-Methyl-N-vanillyl-6-nonenamide; Nonivamide Impurity; Vanillylamide Impurity
EINECS	Contact for details

Quality Control

Every batch of Capsaicin Impurity 2 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use as a reference standard, including chromatographic purity and structural confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity (by HPLC), and impurity profile. Our quality commitment aligns with ICH Q3A/B guidelines for impurities in new drug substances and products.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.